Embolic Microspheres yog compressible hydrogel microspheres nrog cov duab tsis tu ncua, du nto, thiab calibrated loj, uas yog tsim los ntawm kev hloov kho tshuaj ntawm polyvinyl cawv (PVA) cov ntaub ntawv. Embolic Microspheres muaj cov macromer muab los ntawm polyvinyl cawv (PVA), thiab yog hydrophilic, tsis-resorbable, thiab muaj nyob rau hauv ntau qhov ntau thiab tsawg. Cov tshuaj khaws cia yog 0.9% sodium chloride tov. Cov dej ntsiab lus ntawm tag nrho polymerized microsphere yog 91% ~ 94%. Microspheres tuaj yeem tiv taus compression ntawm 30%.
Embolic Microspheres yog npaj los siv rau embolization ntawm arteriovenous malformations (AVMs) thiab hypervascular hlav, nrog rau cov uterine fibroids. Los ntawm kev thaiv cov ntshav mus rau thaj tsam ntawm lub hom phiaj, cov qog los yog malformation yog tshaib plab ntawm cov as-ham thiab shrinks loj.
Hauv tsab xov xwm no, peb yuav qhia koj cov ncauj lus kom ntxaws txog kev siv Embolic Microspheres.
Kev npaj khoom
Nws yog tsim nyog los npaj 1 20ml syringe, 2 10ml syringes, 3 1ml los yog 2ml syringes, peb-txoj kev, txiav txiab, sterile khob, tshuaj kho mob, embolic microspheres, sib piv media, thiab dej rau txhaj.
Kauj Ruam 1: Kho cov tshuaj chemotherapy
Siv txiab txiab los tshem tawm cov tshuaj chemotherapeutic lub raj mis thiab ncuav cov tshuaj chemotherapeutic rau hauv lub khob tsis muaj menyuam.
Hom thiab ntau npaum li cas ntawm cov tshuaj chemotherapeutic yog nyob ntawm qhov kev xav tau ntawm kev kho mob.
Siv dej rau kev txhaj tshuaj kom yaj cov tshuaj tua kab mob, thiab qhov pom zoo pom zoo yog ntau dua 20mg / ml.
ATom qab cov tshuaj chemotherapeutic tau yaj tag, cov tshuaj chemotherapeutic tshuaj tau muab rho tawm nrog 10ml syringe.
Kauj Ruam 2: Extraction ntawm cov tshuaj nqa embolic microspheres
Cov embolized microspheres tau shaken tag nrho, muab tso rau hauv ib lub koob txhaj tshuaj kom sib npaug lub siab hauv lub raj mis,thiab tshem tawm cov tshuaj thiab microspheres los ntawm lub raj mis cilin nrog 20ml syringe.
Cia lub syringe sawv ntsug rau 2-3 feeb, thiab tom qab lub microspheres nyob, lub supernatant raug thawb tawm ntawm cov tshuaj.
Kauj Ruam 3: Xa cov tshuaj Chemotherapeutic rau hauv Embolic Microspheres
Siv 3 txoj kev stopcock los txuas cov koob txhaj tshuaj nrog lub embolic microsphere thiab cov koob txhaj tshuaj nrog cov tshuaj tua kab mob, xyuam xim rau kev sib txuas ruaj khov thiab cov kev taw qhia ntws.
Thawb cov tshuaj tua kab mob syringe nrog ib txhais tes, thiab rub lub syringe uas muaj embolic microspheres nrog rau lwm cov tes. Thaum kawg, cov tshuaj chemotherapy thiab microsphere yog sib xyaw rau hauv 20ml syringe, co lub syringe kom zoo, thiab tawm rau 30 feeb, co txhua 5 feeb thaum lub sij hawm lub sij hawm.
Kauj ruam 4: Ntxiv qhov sib piv media
Tom qab cov microspheres tau ntim nrog cov tshuaj chemotherapeutic rau 30 feeb, qhov ntim ntawm cov tshuaj raug xam.
Ntxiv 1-1.2 npaug ntawm qhov ntim ntawm tus neeg sawv cev zoo sib xws los ntawm peb txoj kev stopcock, co zoo thiab cia sawv ntsug rau 5 feeb.
Kauj Ruam 5: Microspheres yog siv rau hauv cov txheej txheem TACE
Los ntawm peb txoj kev stopcock, txhaj li 1ml ntawm microspheres rau hauv 1ml syringe.
Cov microspheres tau txhaj rau hauv microcatheter los ntawm kev txhaj tshuaj pulsed.
Qhia kev saib xyuas:
Thov xyuas kom muaj kev ua haujlwm aseptic.
Paub meej tias cov tshuaj chemotherapeutic yog yaj tag ua ntej thauj cov tshuaj.
Qhov concentration ntawm cov tshuaj chemotherapy yuav cuam tshuam rau cov tshuaj loading nyhuv, qhov siab dua qhov concentration, qhov ceev ntawm adsorption tus nqi, cov tshuaj pom zoo loading concentration yog tsis tsawg tshaj li 20mg / ml.
Tsuas yog cov dej tsis huv rau kev txhaj tshuaj lossis 5% kev txhaj tshuaj qabzib yuav tsum tau siv los ua kom cov tshuaj tua kab mob.
Tus nqi ntawm doxorubicin dissolution hauv cov dej tsis muaj menyuam rau kev txhaj tshuaj yog me ntsis sai dua 5% qabzib txhaj tshuaj.
5% qabzib txhaj tshuaj yaj pirarubicin me ntsis sai dua li cov dej tsis huv rau kev txhaj tshuaj.
Kev siv ioformol 350 raws li qhov sib piv nruab nrab yog qhov muaj txiaj ntsig zoo rau kev ncua ntawm microspheres.
Thaum txhaj rau hauv cov qog los ntawm microcatheter, kev txhaj tshuaj mem tes yog siv, uas yog qhov zoo dua rau kev tshem tawm microsphere.
Post lub sij hawm: Feb-28-2024